Meet the compassionate and dynamite Afro chick Sandra (Mittie Lawrence), the foxy blonde Janis (Alana Stewart), and the cute brunette Barbara (Patti Byrne) in, Night Call Nurses. They are a fun trio serving as student nurses in a California hospital, run by a racist superintendent. Their chief nemesis is the stern head nurse, who despises their sexual shenanigans. Soul sister Sandra, guilty over witnessing the suicide of a patient, helps out a framed black activist (Stack Pierce) in the prison ward. Janis helps a speed freak truck driver come down off his high and falls head over heels for him. Barbara takes time off in a hippie encounter group that messes with her mind. These nurses put goofy orderlies in their place, scare off slimy medicine salesmen, and stand up to the man whenever they get a chance.